Sandboxie Plus

Sandboxie Plus is sandbox-based isolation software for 32- and 64-bit Windows NT-based operating systems. It creates a sandbox-like isolated operating environment in which applications can be run or installed without permanently modifying the local or mapped drive. An isolated virtual environment allows controlled testing of untrusted programs and web surfing.
Sandboxie Plus is being developed by David Xanatos since it became open source, before that it was developed by Sophos under the name Sandboxie.

Sandboxie runs your programs in an isolated space which prevents them from making permanent changes to other programs and data in your computer. Secure Web Browsing: Running your Web browser under the protection of Sandboxie means that all malicious software downloaded by the browser is trapped in the sandbox and can be discarded trivially. Enhanced Privacy: Browsing history, cookies, and cached temporary files collected while Web browsing stay in the sandbox and don’t leak into Windows. 16 languages. Secure E-mail: Viruses and other malicious software that might be hiding in your email cant break out of the sandbox and cant infect your real system. Windows Stays Lean: Prevent wear-and-tear in Windows by installing software into an isolated sandbox.

Source: https://github.com/sandboxie-plus/Sandboxie